Yale recently digitized and released over 170,000 photos taken by the Farm Security Administration during the Great Depression, and 331 of them were from Buffalo and Erie County. The photos, which primarily document the lives of everyday laborers and their families in Buffalo, were originally meant to gin up support for New Deal-style government programs, many of which had just been thrown out by the courts.
The interactive map is so cool.
Search old historical areas of your families or where you want to see how it used to look. I found this one searching my county in Louisville (Jefferson county) and its by the MIssissippi river! How cool!